Reaction negative_influence su_wca1_s_wca2_re66 map

APC|​K63_ubi:​AXIN*:​CK1_alpha_*:​GSK3*@Cytoplasm map → WNT canonical pathway@Cytoplasm map

No reaction regulators

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map

References
The destruction is part of the canonical wnt pathway when no WNT ligand is bound to the receptor. This complex makes sure that beta-catenin is degraded.