Reaction dissociation su_mpk1_mpk1_re67
GRB2:RAS*|pho:RTK*:SOS*@Plasma Membrane
→ RAS*@Plasma Membrane
+ GRB2:RTK*:SOS*@Plasma Membrane
Reaction regulators:
- Unknown_catalysis
- RASA4@Plasma Membrane
References
Calcium activates the Ras GAP CAPRI (RASA4) that translocates to the PM and downregulates any Ras that is activated on this compartment by the exchange factor SOS.
PMID:16488589