Reaction heterodimer_association su_mpk1_mpk1_re16
BRAF|pho:GRB2:KSR1:MEK*|pho|pho:RAS*|pho:RTK*:SOS*@Plasma Membrane
+
ERK*@Cytoplasm
→
BRAF|pho:ERK*|pho|pho:GRB2:KSR1:MEK*|pho|pho:RAS*|pho:RTK*:SOS*@Plasma Membrane
No reaction regulators
References
ERK recruitment is enhanced by KSR1. ERK is then phosphorylated by MEK.
PMID:19541618
+ ERK*@Cytoplasm → BRAF|pho:ERK*|pho|pho:GRB2:KSR1:MEK*|pho|pho:RAS*|pho:RTK*:SOS*@Plasma Membrane