Identifiers
integrin subunit alpha 1
HUGO:ITGA1 hgnc_id:HGNC:6134 HGNC:6134 ENTREZ:3672 UNIPROT:P56199
HUGO:ITGA1
integrin, alpha 1
HUGO:ITGA1 HGNC:6134 ENTREZ:3672 UNIPROT:P56199
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
EMT Senescence / CELL_MATRIX_ADHESIONS
EMT Senescence / ECM
References
CASCADE:INTEGRIN
PMID:26148229
Fibroblasts express the ??1??1, ??2??1 and ??11??1 collagen-binding integrins
PMID:19397781
alpha(1)beta(1) integrin is of importance not only for the differentiation of mesenchymal cells into myofibroblasts but also for the neovascularization and connective tissue organization and emphasize the importance of myofibroblasts in the pathophysiology of tissue repair, inflammation and tumour growth.