Protein MYL12A map

Identifiers
myosin light chain 12A
HUGO:MYL12A hgnc_id:HGNC:16701 HGNC:16701 ENTREZ:10627 UNIPROT:P19105
myosin, light chain 12A, regulatory, non-sarcomeric
"myosin, light polypeptide, regulatory, non-sarcomeric (20kD)"
HUGO:MYL12A HGNC:16701 ENTREZ:10627 UNIPROT:P19105

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / FIBROBLAST_ACTIVATION_MARKERS  map
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CYTOSKELETON_POLARITY  map

References
PMID:21674557
Tumor-secreted lysophostatidic acid accelerates hepatocellular carcinoma progression by promoting differentiation of peritumoral fibroblasts in myofibroblasts.
This effect is mediated by up-regulation of specific genes related to a myo/contractile phenotype (ACTA2, CNN1,FN (ED-A containing), EDN1, MYL12A, TAGLN2) and inhibition of ACTG2 expression.

Modifications:
In compartment: Cytosol
  1. MYL12A@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rMYL12A@Cytosol map → map MYL12A@Cytosol map
    2. MYL12A@Cytosol map → map MARKERS_OF_FIBROBLAST_ACTIVATION@default map
    3. MyosinLC*@Cytosol map → map MYL12A@Cytosol map
    As Catalyser: