Protein ACTG2 map

Identifiers
actin, gamma 2, smooth muscle, enteric
HUGO:ACTG2 hgnc_id:HGNC:145 HGNC:145 ENTREZ:72 UNIPROT:P63267

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / FIBROBLAST_ACTIVATION_MARKERS  map
 Cancer Associated Fibroblasts  map  / MOTILITY  map

References
PMID:21674557
Tumor-secreted lysophostatidic acid accelerates hepatocellular carcinoma progression by promoting differentiation of peritumoral fibroblasts in myofibroblasts.
This effect is mediated by up-regulation of specific genes related to a myo/contractile phenotype (ACTA2, CNN1,FN (ED-A containing), EDN1, MYL12A, TAGLN2) and inhibition of ACTG2 expression.

Modifications:
In compartment: Cytosol
  1. ACTG2@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. ACTG2@Cytosol map → map Actin cytoskeletal*@Cytosol map
    2. rACTG2@Cytosol map → map ACTG2@Cytosol map
    As Catalyser: