Identifiers
CDC42 small effector 1
HUGO:CDC42SE1 HGNC:17719 ENTREZ:56882 UNIPROT:Q9NRR8

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence   / EMT_REGULATORS 
 EMT Senescence   / CYTOSKELETON_POLARITY 

References
PMID:10816584
PMID:17045588
CDC42SE1 (SPEC1) binds to CDC42 and supresses CDC42-induced JNK activation and cytoskeleton remodeling.

References
em_emtc_emtc_re844( EMT Senescence  ):
PMID:10816584
PMID:17045588
CDC42SE1 (SPEC1) binds to CDC42 and supresses CDC42-induced JNK activation and cytoskeleton remodeling.
PMID:9113980
RhoGDI (so-called ARHGDIA) and GDIG4 (so-called ARHGDIB) are two known GDIs for the Rho-subfamily of GTPases.
ARHGDIG is about 50 percent identical to ARHGDIA and ARHGDIB. ARHGFIG binds to CDC42 and RhoA with less affinity compared with ARHGDIA and does not bind with Rac1, Rac2, or Ras.
ARHGDIG functions as a GDI for CDC42 but with about 20 times less efficiency than ARHGDIA.
PMID:9490022
ARHGDIA,B,G are CDC42_GDIs

1. CDC42SE1@Cytosol

1. em_emtc_emtc_s3012 → em_emtc_emtc_s3011