Protein HAS2 map

Identifiers
hyaluronan synthase 2
HUGO:HAS2 hgnc_id:HGNC:4819 HGNC:4819 ENTREZ:3037 UNIPROT:Q92819

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / MATRIX_REGULATION  map
 RECON2  map

References
PMID:20823158
CAFs have been identified as a source of hyaluronan, and genetic ablation of the hyaluronan synthase gene (Has2) in fibroblasts strongly diminishes the entry of macrophages into the tumour microenvironment.

Modifications:
In compartment: Cytosol
  1. HAS2@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. hyaluronan@Cytosol map → map hyaluronan@default map