Reaction state_transition rc_re1541 map

ITCH@Cytosol map → ITCH|​pho@Cytosol map

Reaction regulators:
Catalysis
  1. JNK1*|​pho|​active@Cytosol map


References
PMID:16469705
The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover.