Reaction state_transition rc_re1529 map

Drp1*|​pho@Cytosol map → Drp1*@Cytosol map

Reaction regulators:
Catalysis
  1. GLUD1:​GLUL:​MLKL|​S358_pho|​T357_pho:​PGAM5|​pho:​PYGL:​RIPK1|​S161_pho:​RIPK3|​S199_pho|​S227_pho@Cytosol map


References
PMID:23073834
PGAM5L/PGAM5S activate the mitochondrial fission regulator Drp1 by dephosphorylation, thus leading to mitochondrial fission.
PMID:22265414
PGAM5S recruited the mitochondrial fission factor Drp1 and activated its GTPase activity by dephosphorylating the serine 637 site of Drp1