Reaction state_transition rc_re1409 map

BCL2@Mitochondrial inner membrane map BCL2|​pho@Mitochondrial inner membrane map

Reaction regulators:
Catalysis
  1. PRKCA@Cytosol map
  2. ERK*@Cytosol map
  3. JNK*|​Y185_pho@Cytosol map


References
PMID:9115213
S70 phosphorylation of BCL2 necessary for its antiapoptotic function
in NSF/N1.H7 mouse leukemia cells BCL2 mutants transfection) in response to IL-3, etoposide, or bryostatin-1, a PKC activator
PMID:9738012
suggest that PRKCA is the main PRKC BCL2 kinase in HL60 human acute myeloid leukemia cell line
PMID:10677502
ERK1/2 is a BCL2 S70 kinase in NSF/N1.H7 cells stimulated with IL-3
in vitro direct phosphorylation
PMID:11323415
JNK is a BCL2 S70 kinase in NSF/N1.H7 cells upon IL-3 withdrawal