Reaction state_transition rc_re1331 map

RIPK1|​K377_ubi@TNFRSF1 Receptor Complex map → RIPK1@TNFRSF1 Receptor Complex map

Reaction regulators:
Boolean_logic_gate_and
  1. ITCH|​unk@Cytosol map and RNF11@Cytosol map and TAX1BP1@Cytosol map and TNFAIP3@Cytosol map
Catalysis
  1. CYLD@Cytosol map
  2. TNFAIP3@Cytosol map
  3. ITCH|​unk@Cytosol map
  4. RNF11@Cytosol map
  5. TAX1BP1@Cytosol map


References
PMID:19131965
role of RNF11 in the A20 complex
PMID:23010170
CYLD is required for necroptosis induction by deu-
biquitinating RIP1