Reaction state_transition rc_re331 map

FOXO*@Cytosol map FOXO*|​pho|​pho@Cytosol map

Reaction regulators:
Catalysis
  1. AKT*|​S473_pho|​T308_pho@Cytosol map
  2. PIM*@Cytosol map


References
PMID:10102273
in vitro, by Akt, phosphosites identified by mutagenesis
in 293T using phosphoFOXO1 antibodies
PMID:18593906
in HEK293T, by PIM1s isoform, FOXO3 phosphorylated and inactivated. Phosphomutant of FOXO3 is not phosphorylated and the expression of a reporter gene is not inhibited.