Identifiers
HUGO:IQGAP1
IQ motif containing GTPase activating protein 1
HUGO:IQGAP1 HGNC:6110 ENTREZ:8826 UNIPROT:P46940 GENECARDS:IQGAP1 REACTOME:381664 KEGG:8826 ATLASONC:GC_IQGAP1 WIKI:IQGAP1
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Adaptive Immune Response / TCR_SIGNALING
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / CELL_CELL_ADHESIONS
EMT Senescence / ADHERENS_JUNCTIONS
EMT Senescence / EMT_REGULATORS
EMT Senescence / LYSOSOME_ENDOSOME
HMC:EVADING_GROWTH_SUPPRESSORS
Survival / WNT_NON_CANONICAL
References
PMID:22573807
PMID:15263019
Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments.