Protein MLST8 map

Identifiers
HUGO:MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
HUGO:MLST8 HGNC:24825 ENTREZ:64223 UNIPROT:Q9BVC4
HUGO:MLST8 HGNC:24825 ENTREZ:64223 UNIPROT:Q9BVC4 GENECARDS:MLST8 REACTOME:355793 KEGG:64223 WIKI:MLST8

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / TCR_SIGNALING  map
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / CORE  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / FATTY_ACID_BIOSYNTHESIS  map
 Regulated Cell Death  map  / MOMP_REGULATION  map
 Regulated Cell Death  map  / RCD_GENES  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:16469695 PMID:26159692 PMID:23087689
PMID:16469695, PMID:26159692
mTOR Complex 1 (mTORC1) is composed of mTOR itself, regulatory-associated protein of mTOR (Raptor), mammalian lethal with SEC13 protein 8 (MLST8) and the recently identified PRAS40 and DEPTOR
PMID:17680028
PMID:12408816

Modifications:
Participates in complexes:
In compartment: T_cell
  1. MAPKAP1:​MLST8:​MTOR:​PRR5:​RICTOR@T_cell map
  2. DEPTOR:​MLST8:​MTOR:​PRAS40*:​RPTOR@T_cell map
  3. (DEPTOR:​MLST8:​MTOR|​pho:​PRAS40*:​RPTOR)|​active@T_cell map
Participates in reactions:
As Reactant or Product:
  1. DEPTOR:​MLST8:​MTOR:​PRAS40*:​RPTOR@T_cell map → map (DEPTOR:​MLST8:​MTOR|​pho:​PRAS40*:​RPTOR)|​active@T_cell map
As Catalyser:
  1. gFOXP3@T_cell map → map rFOXP3@T_cell map
  2. AKT*@T_cell map → map AKT*|​Thr450_pho@T_cell map
  3. AKT*|​Thr308_pho|​Thr450_pho@T_cell map → map AKT*|​Thr308_pho|​ser473_pho|​Thr450_pho|​active@T_cell map