Protein CD11a*
Identifiers
HUGO:ITGAL
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Adaptive Immune Response
/ SMAC
Innate Immunity
/ INTEGRINS
References
PMID:2150484
CASCADE:LFA1
NATURAL_KILLER
PMID:10591186, PMID:24440149
LFA1 physically associates with DNAM1 in NK cells.
Phosphorylated by PKC S329 probably plays a critical role in this association.
Modifications:
Participates in complexes:
In compartment: pSMAC
- CD11a*:CD18*@pSMAC
- CD11a*:CD18*:ICAM1:TLN1@pSMAC
Participates in reactions:
As Reactant or Product:- CD11a*:CD18*@pSMAC
+ ICAM1@Cancer_cell
+ TLN1@pSMAC
→
CD11a*:CD18*:ICAM1:TLN1@pSMAC
As Catalyser:- TUBGCP2:TUBGCP3:TUBGCP4:TUBGCP5:TUBGCP6:Tubulin-_alpha_*:Tubulin-_beta_*:Tubulin-_gamma_*@T_cell
+ PXN|pho@T_cell
→
PXN:TUBGCP2:TUBGCP3:TUBGCP4:TUBGCP5:TUBGCP6:Tubulin-_alpha_*:Tubulin-_beta_*:Tubulin-_gamma_*@T_cell