Protein RHEB map

Identifiers
HUGO:HREB
HUGO:RHEB
Ras homolog enriched in brain
HUGO:RHEB HGNC:10011 ENTREZ:6009 UNIPROT:Q15382
HUGO:RHEB HGNC:10011 ENTREZ:6009 UNIPROT:Q15382 GENECARDS:RHEB REACTOME:63056 KEGG:6009 ATLASONC:GC_RHEB WIKI:RHEB
Q15382

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / TCR_SIGNALING  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Innate Immunity  map  / IMMUNOSTIMULATORY_CORE_PATHWAYS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:12906785 PMID:19022819 PMID:23087689
 DENDRITIC_CELL  map
 NATURAL_KILLER  map
PMID:12906785, PMID:19022819
AKT activates Rapamycin associated protein FRAP2 ( mTOR ) probably through Tuberin/GTP-binding protein Ras homolog enriched in brain ( RHEB ) pathway.
PMID:19143635
PMID:18466115

Modifications:
Participates in complexes:
In compartment: T_cell
  1. GDP:​RHEB@T_cell map
  2. (GTP:​RHEB)|​active@T_cell map
Participates in reactions:
As Reactant or Product:
  1. (GTP:​RHEB)|​active@T_cell map + GDP@T_cell map → map GDP:​RHEB@T_cell map + GTP@T_cell map
As Catalyser:
  1. DEPTOR:​MLST8:​MTOR:​PRAS40*:​RPTOR@T_cell map → map (DEPTOR:​MLST8:​MTOR|​pho:​PRAS40*:​RPTOR)|​active@T_cell map