Identifiers
HUGO:PPP3CA HGNC:9314 ENTREZ:5530 UNIPROT:Q08209 GENECARDS:PPP3CA HUGO:PPP3CB HGNC:9315 ENTREZ:5532 UNIPROT:P16298 GENECARDS:PPP3CB HUGO:PPP3CC HGNC:9316 ENTREZ:5533 UNIPROT:P48454 GENECARDS:PPP3CC
protein phosphatase 3, catalytic subunit, alpha isozyme
CALN, CALNA, "protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform", "protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)"
HUGO:PPP3CA HGNC:9314 ENTREZ:5530 UNIPROT:Q08209 GENECARDS:PPP3CA REACTOME:61110 KEGG:5530 ATLASONC:GC_PPP3CA WIKI:PPP3CA
protein phosphatase 3, catalytic subunit, beta isozyme
CALNB, "protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform", "protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta)"
HUGO:PPP3CB HGNC:9315 ENTREZ:5532 UNIPROT:P16298 GENECARDS:PPP3CB REACTOME:403037 KEGG:5532 ATLASONC:GC_PPP3CB WIKI:PPP3CB
protein phosphatase 3, catalytic subunit, gamma isozyme
"protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform", "protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma)"
HUGO:PPP3CC HGNC:9316 ENTREZ:5533 UNIPROT:P48454 GENECARDS:PPP3CC REACTOME:61114 KEGG:5533 ATLASONC:GC_PPP3CC WIKI:PPP3CC
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Adaptive Immune Response / TCR_SIGNALING
Innate Immunity / IMMUNOSTIMULATORY_CORE_PATHWAYS
HMC:EVADING_GROWTH_SUPPRESSORS
Survival / WNT_NON_CANONICAL
References
PMID:10089876 PMID:7650486 PMID:9973469 PMID:21199863
protein phosphatase 3, catalytic subunit, alpha isozyme
CALN, CALNA, "protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform", "protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)"
REACTOME:61110 KEGG:5530 ATLASONC:GC_PPP3CA WIKI:PPP3CA
protein phosphatase 3, catalytic subunit, beta isozyme
CALNB, "protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform", "protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta)"
REACTOME:403037 KEGG:5532 ATLASONC:GC_PPP3CB WIKI:PPP3CB
protein phosphatase 3, catalytic subunit, gamma isozyme
"protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform", "protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma)"
REACTOME:61114 KEGG:5533 ATLASONC:GC_PPP3CC WIKI:PPP3CC
CASCADE:Fc_gamma_RIII
NATURAL_KILLER
PMID:10089876, PMID:7650486, PMID:9973469
??Ca('2+)??activates Calmodulin 2 (??Calmodulin??)/ Protein phosphatase 3 (Calcineurin??) signal. Activated??Calcineurin??dephosphorylates Nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 2 (??NF-AT1(NFATC2)??).??
This signaling is activated downstream of CD16 in NK cells