Protein LAMA* map

Identifiers
laminin subunit alpha 1
HUGO:LAMA1 hgnc_id:HGNC:6481 HGNC:6481 ENTREZ:284217 UNIPROT:P25391
laminin subunit alpha 2
HUGO:LAMA2 hgnc_id:HGNC:6482 HGNC:6482 ENTREZ:3908 UNIPROT:P24043
laminin subunit alpha 3
HUGO:LAMA3 hgnc_id:HGNC:6483 HGNC:6483 ENTREZ:3909 UNIPROT:Q16787
laminin subunit alpha 4
HUGO:LAMA4 hgnc_id:HGNC:6484 HGNC:6484 ENTREZ:3910 UNIPROT:Q16363
laminin subunit alpha 5
HUGO:LAMA5 hgnc_id:HGNC:6485 HGNC:6485 ENTREZ:3911 UNIPROT:O15230

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / MATRIX_REGULATION  map

References
CASCADE:INTEGRIN
PMID:26519775
a3b1 integrin is a Laminin receptor
PMID:16572188
Fibroblasts synthesize many of the constituents of the fibrillar ECM such as type I (genes COL1A1, COL1A2), type III (COL3A1) and type V collagen (COL5A1, COL5A2, COL5A3), and fibronectin.
They also contribute to the formation of basement membranes by secreting type IV collagen (COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6) and laminin.

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. LAMA*:​LAMB*:​LAMC*@Cytosol map
In compartment: default
  1. LAMA*:​LAMB*:​LAMC*@default map
Participates in reactions:
As Reactant or Product:
  1. LAMA*:​LAMB*:​LAMC*@Cytosol map → map LAMA*:​LAMB*:​LAMC*@default map
  2. LAMA*:​LAMB*:​LAMC*@Cytosol map → map formation of basement membrane@Cytosol map
As Catalyser:
  1. ca_s4784 → map ca_s4784