Reaction state_transition su_akt1_s_akt1_re82 map

PTEN|​S370_pho@Cytoplasm map → PTEN|​S370_pho|​T366_pho@Cytoplasm map

Reaction regulators:
Catalysis
  1. GSK3_beta_*@Cytoplasm map


Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:17444818
ANNOTATION:PTEN is destabilized by phosphorylation on T366 followed by phosphorylation on S370 by GSK3beta.