Reaction heterodimer_association su_mpk1_mpk1_re138 map

MAP3K1@Cytoplasm map + RIPK1:​TNFRSF1A:​TRADD:​TRAF2@Plasma Membrane map → MAP3K1|​pho:​RIPK1:​TNFRSF1A:​TRADD:​TRAF2@Cytoplasm map

No reaction regulators

References
MEKK1 is significantly activated by TNF. Oligomerisation of TRAFs is sufficient to trigger MEKK1 binding. MEKK1 associates selectively with oligomerised TRAF2 in vivo in a TNF-dependent manner.
PMID:11274345