Reaction state_transition su_mpk1_mpk1_re94 map

RSK*@Cytoplasm map → RSK*|​pho@Cytoplasm map

Reaction regulators:
Catalysis
  1. ERK*|​pho|​pho|​hm2:​MEK*|​pho|​pho:​SEF*@Cytoplasm map
  2. ERK*|​pho|​pho|​hm2:​MEK*|​pho|​pho:​_beta_-Arrestin2*@Cytoplasm map


References
RSK2 is a well known ERK substrate in the cytoplasm and has been shown to undergo autophosphorylation after ERK phosphorylation.
RSKs interact with ERK and dissociate upon activation.
Results suggested that KSR1 was the scaffold utilised by ERK1/2 for activating cPLA2 but not RSK1.
PMID:15239952 PMID:15187187 PMID:19114553