Reaction transport su_mpk1_mpk1_re65 map

ERK*|​pho|​pho@Cytoplasm map → ERK*|​pho|​pho@Nucleus map

Reaction regulators:
Catalysis
  1. p38*@Cytoplasm map


References
Mxi2 is a splicing isoform of P38. It directly interacts with ERK1/2. Mxi2 prolongs ERK activation (in the nucleus) by binding.
Mxi2 could suffice to promote the transport of ERK1/2 to the nucleus in the absence of further stimulation.
PMID:12697810 PMID:17255949