Reaction state_transition su_mpk1_mpk1_re32 map

Caspase9*@Cytoplasm map → Caspase9*|​pho@Cytoplasm map

Reaction regulators:
Catalysis
  1. ERK*|​pho|​pho@Cytoplasm map


References
Caspase9 is phosphorylated on Thr125 in a MEK1/2-dependent manner in vivo. Furthermore caspase9 is efficiently phosphorylated on Thr125 by ERK in vitro suggesting that it is targeted directly by ERK in vivo. This is one of the ways ERK plays its anti-apoptotic role.
PMID:12792650