Reaction state_transition rc_re1706 map

AKT*@Cytosol map → AKT*|​S473_pho|​T308_pho@Cytosol map

Reaction regulators:
Catalysis
  1. PDPK1:​PIP3*@Cytosol map


References
PMID:19203586
PHLDA3 competes with the PH domain of Akt for binding of membrane lipids, thereby inhibiting Akt translocation to the cellular membrane and activation
PMID:15718470
TORC2 complex as AKT S473 kinase
PMID:17604717
PDK1 phosphorylates the activation loop of AKT at T308